Hand, Foot, and Mouth Disease (HFMD) is a common viral disease, caused by a virus belongs to a group of Enterovirus, that usually spreads in rainy season and affects children younger than 5 years old. This contagious disease can be trans- mitted by contact with patient’s nose or throat secretions, blister fluid or feces. Infected person often have a fever, a pain around or inside the mouth with lesions and also skin rash, sometimes with blisters on the palms, soles. Commonly, these symptoms should recover within 7 – 10 days.
Among Enterovirus group, coxsackie A16 and enterovirus 71 are two most common viruses in Thailand that caused the disease. Enterovirus 71 has been associated with severe symptoms and neurological complications such as en- cephalitis, meningitis, myocarditis and shock which may lead to death. Therefore, the fast and accurate diagnosis could prevent severe events.
Laboratory diagnosis of Hand, Foot, and Mouth Disease (HFMD)
Various lab tests are available at N Health including detections of Enterovirus genetic materials which are able to classify virus species. A high sensitivity and specificity Real-time PCR method can detect the virus in early phase of infection and the result can be used for monitoring of severity or complications that might occur.
The test should be under the discretion of a physician. | The mentioned test is performed by the laboratory with ISO 15189 certification and lab accreditation. **Above turnaround time does not include logistic time. For BDMS network hospitals, please contact N Health laboratory located at your hospitals.
Hye Kyung Cho, M.D.,1 Na Yong Lee, M.D.,1 Hyunju Lee, M.D.,et al. Enterovirus 71-associated hand, foot and mouth diseases with neurologic symptoms, a university hospital experience in Korea, 2009. Korean J Pediatr. 2010 May; 53(5): 639–643.