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N Test

18 December 2018

TUBERCULOSIS


Tuberculosis (TB) is an infectious disease caused by the bacterium, Mycobacterium tuberculosis (MTB). Tuberculosis generally

dominates lungs, however the disease also affect other parts of the body including lymph nodes and gastrointestinal tract. WHO

reported in 2015, there were an estimated 10.4 million new TB cases worldwide and 1.8 million people died from TB. In Thailand,

there are approximately 117,000 new cases or at the incident rate of 172 case per 100,000 population.


The QuantiFERON-TB is a blood test for use as an aid in diagnosing Mycobacterium tuberculosis infection, including latent

tuberculosis infection and tuberculosis disease. Blood samples are mixed with TB antigens and controls. If the patient is

infected with M. tuberculosis, their white blood cells will release IFN-gamma in response to the TB antigens. The interpretations

of the results are based on the amount of IFN-gamma that is released in response to the antigens. If the test result is positive,

patient should be tested for further examination such as TB cul ture, PCR or chest X-ray.

Because you should to differentiate between latent TB or active TB.


Advantages of the test are

• Requires a single patient visit to draw a blood sample.

• Does not boost responses measured by subsequent tests, which can happen with tuberculin skin tests (TST).

• Is not subject to reader bias that can occur with Tuberculin Skin Test.

• Is not affected by prior BCG (bacille Calmette-Guérin) vaccination.

* This operation schedule is for the test performed at N Health head quarter, Bangkok .

** Above turnaround time does not include logistic time. For BDMS network hospitals, please contact N Health laboratory located at your hospitals.

*** For BDMS Network

**** For Commercial Customers (Advance payment for special tube at customer service)

References

1 http://www.who.int/tb/publications/factsheet_global.pdf?ua=1

2 http://www.who.int/tb/publications/global_report/en/

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