Tests and Procedures

Our Clinical Laboratory Services cover diversified diagnoses that patients and physicians need in making healthcare decisions such as

Find a test or procedure by its first letter

Find a test or procedure by its first letter

Find a test or procedure by its first letter

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C911 : Apolipoprotein B

Comment

Test Code
C911
Test Name
Apolipoprotein B
Department
Biochemistry
Sample Type/Volume
serum 1 ml
Storage Condition
2-8 °C
Collection Remark
-
Principle
-
Method
immunoturbidity
Reference Range
Men : 66‑133 mg/dL Women : 60‑117 mg/dL
Clinical

Apolipoprotein B (APO B) has been reported to be a powerful

indicator of CAD. In some patients with CAD, APO B is elevated even in the presence of normal LDL cholesterol.

Apolipoprotein B (ApoB) is the primary protein component of low-density lipoprotein (LDL). LDL contains a variable amount of cholesterol, but each LDL contains exactly 1 ApoB protein. Therefore, ApoB is a superior indicator of circulating LDL compared to LDL cholesterol (LDL-C). ApoB has been demonstrated to perform equally with LDL particles measured by nuclear magnetic resonance spectroscopy.(1)

ApoB is strongly associated with increased risk of developing cardiovascular disease (CVD) and often outperforms LDL-C at predicting risk of coronary heart disease.(2-4) Patients with acceptable non-HDL-C (or LDL-C) but elevated ApoB remain at higher risk of developing CVD; conversely, patients with acceptably low ApoB but moderate non-HDL-C or LDL-C elevations are at a reduced risk for CVD.(5,6) Finally, in 7 different placebo-controlled randomized clinical trials, on-statin reduction of ApoB was more closely related to CVD risk reduction than non-HDL-C or LDL-C.(7)

Turnaround Time
1 day
Operation Schedule
Daily