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K370 : ADAMTS 13 (Chula)

Comment

Test Code
K370
Test Name
ADAMTS 13 (Chula)
Department
Coagulation
Sample Type/Volume
Na Citrate plasma 1 ml x 2 tubes
Storage Condition
Freeze
Collection Remark
-
Principle
-
Method
ELISA
Reference Range
-
Clinical
ADAMTS 13 is enzyme for cut von Willebrands factor, If lack ADAMTS13 TTP are occur
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ADAMTS-13 is a metalloprotease that limits platelet-rich thrombus formation in arterioles by cleaving von Willebrand factor (VWF) at its Tyr 1605–Met 1606 bond. Deficiency of ADAMTS-13 activity, either because of an inherited or an acquired etiology, may lead to a potentially lethal syndrome, thrombotic thrombocytopenic purpura (TTP).
Thrombotic thrombocytopenic purpura (TTP), a rare but life threatening disease characterized by microangiopathic haemolytic anaemia and consumptive thrombocytopenia leading to disseminated microvascular thrombosis and variable signs and symptoms of organ ischemia and damage.
( Journal of Thrombosis and Haemostasis, 8: 631–640)
Turnaround Time
16 days
Operation Schedule
-