Tests and Procedures

Our Clinical Laboratory Services cover diversified diagnoses that patients and physicians need in making healthcare decisions such as

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Find a test or procedure by its first letter

Find a test or procedure by its first letter

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MM986 : ACT BRCA (ACT Genomics)

Comment

Test Code
MM986
Test Name
ACT BRCA (ACT Genomics)
Department
Bio - Molecular Laboratory
Sample Type/Volume
Please provide one of the tumor tissue type (1 of 3) and also provide normal tissue for germ line mutation tests (Send both FFPE and Blood if available) FFPE: 1. Surgical => 5 unstain slides (10 um/slide) + 1 H&E slide 2. Core Needle Biopsies => 6 unstain slides (10 um/slide) + 1 H&E slide 3. DNA > 200 ng Normal: 1. Whole blood 8 ml blood in Strek tube (Deliver within 4 days)
Storage Condition
Room temperature
Collection Remark
Request with Specimen preparation for ACT Test (R023)
Principle
Next Generation Sequencing (NGS)
Method
Next Generation Sequencing (NGS)
Reference Range
-
Clinical
To determine therapeutic implication

General Information :
Breast cancer is the most common cancer in women in the world. Mutations in BRCA1 and BRCA2 have been confirmed to be highly related to breast cancer and ovarian cancer. American Society of Clinical Oncology (ASCO) reported that BRCA mutation carriers have an increased risk of developing breast cancer (54-85%), ovarian cancer (40-60%), prostate cancer (20%), and pancreatic cancer (5%). Research has shown that 8% of the breast cancer patients and 14% of the ovarian cancer patients carry BRCA mutations. Moreover, as many as 50% of the patients with hereditary breast and ovarian cancer syndrome (HBOC) carry BRCA mutations.
Turnaround Time
21 days
Operation Schedule
N/A